The study examined the factors determining clients’ satisfaction with the quality of antiretroviral therapy services in Ekiti State, Nigeria. The research designed used for the study was descriptive design of the survey type. The study targeted PLWHA who assess health care in Ado-Ekiti local government area. The sample size for the study was determined using the formula for calculating single proportion by Abrahamson and Gahlinger. Multistage sampling procedure was used to select the 345 respondents. A semi-structured instrument designed by the researcher was used to collect the needed data for the study. The instrument was validated before administration. The data obtained were analysed using the Statistic Package for Social Sciences (SPSS) where the research questions were answered descriptively through descriptive statistics. The findings of the study revealed that accessibility to care, good perception, quality service and accessible service are major factors determining clients’ satisfaction with the quality of ART services.  In addition, it was revealed that the barriers affecting clients’ satisfaction with the quality of ART services are difficulty asking the doctor questions, feeling that the doctor and client did not understand each other sufficiently, little devotion of time by doctors, difficulty attaining referrals for diagnostic tests and difficulty attaining referrals to specialists. It was recommended among others that there should be creation of social media support groups by health personnel so that clients can share their burdens with one another and improve the level of their interaction.

Keywords: Factors, Satisfaction, Antiretroviral Therapy Services,

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